Carbamic acid, N-[2-hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl]-, 1,1-dimethylethyl ester
N-Boc-2-hydroxy-2-(4-trifluoromethylphenyl)ethanamine
CAS: 864539-94-6
Molecular Formula: C14H18F3NO3
Carbamic acid, N-[2-hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl]-, 1,1-dimethylethyl ester - Names and Identifiers
Carbamic acid, N-[2-hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl]-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C14H18F3NO3 |
| Molar Mass | 305.29 |
Carbamic acid, N-[2-hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl]-, 1,1-dimethylethyl ester - Introduction
N-Boc-2-hydroxy-2-(4-trifluoromethylphenyl)ethanamine is an organic compound with the chemical structure N-tert-butoxymethyl-2-(4-trifluoromethylphenyl)-2-hydroxyethylamine. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
1. nature:
-Appearance: Colorless or yellowish solid.
-Melting point: about 35-40°C.
-Solubility: Good solubility in non-polar solvents, such as chloroform, dimethylformamide, etc.
2. use:
-As an intermediate in organic synthesis, it can be used to prepare a variety of drugs and bioactive molecules.
-Because of its characteristics of controllable blocking protection for organic synthesis, it is often used to protect amine groups.
3. preparation method:
-can be obtained by reacting 2-hydroxyethylamine with a 4-trifluoromethylbenzoic acid ketal (e. g. N-Boc piperazine).
-The reaction occurs at room temperature under an inert atmosphere, and N-Boc protecting groups will be generated.
4. Safety Information:
-The compound has not been publicly reported to be toxic or dangerous.
-But as an organic compound, it may have a certain stimulating effect on the human body or have potential harm to the skin, eyes, respiratory tract, etc.
-When handling this compound, it is recommended to wear appropriate personal protective equipment, such as chemical protective gloves, glasses and respiratory protection. Maintain good ventilation during operation.
1. nature:
-Appearance: Colorless or yellowish solid.
-Melting point: about 35-40°C.
-Solubility: Good solubility in non-polar solvents, such as chloroform, dimethylformamide, etc.
2. use:
-As an intermediate in organic synthesis, it can be used to prepare a variety of drugs and bioactive molecules.
-Because of its characteristics of controllable blocking protection for organic synthesis, it is often used to protect amine groups.
3. preparation method:
-can be obtained by reacting 2-hydroxyethylamine with a 4-trifluoromethylbenzoic acid ketal (e. g. N-Boc piperazine).
-The reaction occurs at room temperature under an inert atmosphere, and N-Boc protecting groups will be generated.
4. Safety Information:
-The compound has not been publicly reported to be toxic or dangerous.
-But as an organic compound, it may have a certain stimulating effect on the human body or have potential harm to the skin, eyes, respiratory tract, etc.
-When handling this compound, it is recommended to wear appropriate personal protective equipment, such as chemical protective gloves, glasses and respiratory protection. Maintain good ventilation during operation.
Last Update：2024-04-09 21:04:16
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